Journal: Metabolites

Article Title: Build, Share and Remix: 3D Printing for Speeding Up the Innovation Cycles in Ambient Ionisation Mass Spectrometry (AIMS)

doi: 10.3390/metabo12020185

Figure Lengend Snippet: 3D printed components (indicated in blue) for ambient ionisation mass spectrometry (AIMS). Desorption electrospray ionisation (DESI) source; digital microfluidics (DMF) chip for automation of sample preparation; 3D printed drift tube for ion mobility spectrometry (IMS); 3D printed low-temperature plasma (3D-LTP) probe; open port probe (OPP) for sampling with spray-based ion source; paper-spray ionisation (PSI) cartridge, supporting the paper tip and facilitating the solvent application.

Article Snippet: Fitting a 3D printed open-port probe (OPP) to a commercial PAL-HTC-xt autosampler (CTC Analytics) increased the sample throughput and method robustness for analysing liquid and solid samples [ ].

Techniques: Mass Spectrometry, Sample Prep, Ion-Mobility Spectrometry, Sampling

Journal: Metabolites

Article Title: Build, Share and Remix: 3D Printing for Speeding Up the Innovation Cycles in Ambient Ionisation Mass Spectrometry (AIMS)

doi: 10.3390/metabo12020185

Figure Lengend Snippet: 3D printed AIMS devices, and their applications. NA—not applicable, ND—not defined. Other abbreviations are listed below.

Article Snippet: Fitting a 3D printed open-port probe (OPP) to a commercial PAL-HTC-xt autosampler (CTC Analytics) increased the sample throughput and method robustness for analysing liquid and solid samples [ ].

Techniques: In Vivo, Imaging, Purification, Ion-Mobility Spectrometry, Sampling

Journal: Metabolites

Article Title: Build, Share and Remix: 3D Printing for Speeding Up the Innovation Cycles in Ambient Ionisation Mass Spectrometry (AIMS)

doi: 10.3390/metabo12020185

Figure Lengend Snippet: Simulation of the electric field strength (V/mm) ( A – D ) and spatial ion traveling ( E , F ) in 3D printed curved electrodes. ( A ) Two turns with two consecutive 45° electrodes; ( B ) four turns with separated 45° electrodes; ( C ) two turns with nine consecutive 10° electrodes; ( D ) 18 separated 10° electrodes. Adapted from , with the permission of Elsevier, copyright 2020. Curved ion focussing electrodes ( E ) with atmospheric collision gas; ( F ) in vaccum. Without collision, ion transmission is prevented. Reprinted from , with permission from the American Chemical Society, copyright 2019.

Article Snippet: Fitting a 3D printed open-port probe (OPP) to a commercial PAL-HTC-xt autosampler (CTC Analytics) increased the sample throughput and method robustness for analysing liquid and solid samples [ ].

Techniques: Transmission Assay

Journal: Metabolites

Article Title: Build, Share and Remix: 3D Printing for Speeding Up the Innovation Cycles in Ambient Ionisation Mass Spectrometry (AIMS)

doi: 10.3390/metabo12020185

Figure Lengend Snippet: Robotic systems with 3D printed components and open-source software. ( A ) Dual robotic arms in front of an ion trap. The arms prepare and deliver the samples. Automation of multiple sample preparation steps with touch and infrared (IR) sensors, water bath and a XYZ stage. Reprinted from , with permission of Elsevier. ( B ) The Robotic Surface Analysis Mass Spectrometry (RoSA-MS), coupled with a 3D surface sampling enables surface contour digitalization and 3D molecular cartography. The RoSA-MS has a modular design allowing modifications for diverse applications. Reprinted from , with the permission of the American Chemical Society, copyright 2018. ( C ) Implementation of the laparoscopic version of the MasSpec Pen, coupled to the da Vinci X Surgical system for in vivo tissue analyses. Reprinted from , with the permission of the American Chemical Society, copyright 2020.

Article Snippet: Fitting a 3D printed open-port probe (OPP) to a commercial PAL-HTC-xt autosampler (CTC Analytics) increased the sample throughput and method robustness for analysing liquid and solid samples [ ].

Techniques: Software, Sample Prep, Mass Spectrometry, Sampling, In Vivo

Journal: Metabolites

Article Title: Build, Share and Remix: 3D Printing for Speeding Up the Innovation Cycles in Ambient Ionisation Mass Spectrometry (AIMS)

doi: 10.3390/metabo12020185

Figure Lengend Snippet: Imaging platforms with 3D printed components. ( A ) LD-LTP MS imaging setup. The system uses a 3D printed holder for the laser and lens, a 3D-LTP probe, and an Open LabBot movement platform. Reprinted from , with the permission of the American Chemical Society, copyright 2019. ( B ) Mounting of a 3D-LTP probe on a Prosolia DESI platform for imaging terpenes, using a 3D printed adapters. ( C ) Adaptation of a commercial Waters DESI-MS for dual-mode (DESI and laser desorption) imaging. Parts in green and the legs for supporting the DESI-MSI platform inside a safety cabin were 3D printed. Reprinted from , with the permission of the American Chemical Society, copyright 2020.

Article Snippet: Fitting a 3D printed open-port probe (OPP) to a commercial PAL-HTC-xt autosampler (CTC Analytics) increased the sample throughput and method robustness for analysing liquid and solid samples [ ].

Techniques: Imaging